DOI: 10.21276/ajptr
Mon, 20 May 2019

Preparation Characterization and Antifungal Activity of Chitosan Thiozole Metal Complex

Mir Shabeer Ahmad1*, Ghulam Mohammad Jan2, G.M.Mir3

1.Govt. Degree College boys kulgam J&K (India)

2.Govt. Degree College Boys anantnag (J&K)

3.Govt. Women's College anantnag J&K(India)


In this paper we synthesized a natural polymer based metal complex. The complex were characterize using different spectrochemical techniques like FT-IR, Mass spectroscopy and X-ray diffraction etc. The complex was found to be active towards different fungal, MIC80 was determined in vitro in liquid medium by the macro broth dilution method as per the guidelines of CLSI reference document M27-A3 for fungi, document NCCLS/CLSI M11-A6 for gram negative bacteria, and document CLSI M100-S15 for gram positive bacteria.  The order of sensitivity to these compounds was C. albicans > E. coli > S. aureus.

Keywords: MIC80, in vitro, X-ray diffraction, gram positive bacteria.

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