DOI: 10.21276/ajptr
Mon, 22 Jul 2019

A Review Study of Infliximab and Methotrexate Use In Management of Rheumatoid Arthritis

Suvarna Laxmi Kodumuru *1,  A. Srinivasa Rao 1,  M. Sri Ram Chandra1

1.Bhaskar Pharmacy College, Department of Pharmacology, Yenkapally Village, Moinabad, Telangana.


The present study is designed to review whether the combination therapy of Infliximab and Methotrexate is better than Methotrexate monotherapy. We have reviewed that combination therapy of TNF-  inhibitors and Methotrexate in RA. How TNF-alpha inhibitors (Infliximab) and Methotrexate performed in randomized controlled trials when compared to Methotrexate in Methotrexate naive Rheumatoid Arthritis patients.

Keywords: Cytokines and inflammatory mediators, Immunology, Rheumatic diseases, Rheumatoid Arthritis (RA), Tissues.


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