Thu, 14 Dec 2017

Metal Complexes of Sulphadiazine Derivative as Reagent and Evaluation of Antibacterial Activity

Ahmed Neamah Thamer Al-Yasiry

The General Directorate of Educational in Najaf Al-Ashraf, Dr. Enad Ghazwan Preparatory School for Boys


ABSTRACT

Synthesis new organic azo dye 4-amino-N-(pyrimidin-2-yl)-3-((4-(N-pyrimidin-2-ylsulfamoyl)phenyl)diazenyl) benzenesulfonamide as reagent (SA) and Study some Analytical properties of Co(II) and Ni(II) metals complexes .The azo dye compound and its complexes were characterized by elemental analysis (C.H.N.S), Uv-Vis, FT- IR, 1H-NMR and measurements of molar conductivity. The data show that the complexes of Co(II) and Ni(II) metals  have the composition of [MR]X2 type. Octahedral environment is suggested for metal complexes. The synthesized compounds were screened against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus for antibacterial activity.

Keywords: Sulfadiazine, Azo, antibacterial activity and complexes

 


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