Tue, 19 Dec 2017

Evaluation of Analgesic Activity of Crude Hydro-Alcoholic Extract of Acacia Senegal Pod

 Rishi Pal2, Rohtash Singh1Mangal Sain Hooda*1

1. Janta College of Pharmacy, Butana, (Sonepat), 131302. Haryana, India.

2. HIMT College of Pharmacy, Greater Noida, Gautam Buddh Nagar (U.P)


ABSTRACT

The main objective of the present investigation is to evaluate the analgesic activity of hydro-alcoholic extract of Acacia Senegal pod on mice. Analgesic activity of hydro-alcoholic extract of Acacia Senegal pod at a dose of 200 mg/Kg, 400 mg /Kg and 800 mg /Kg were evaluated against drug pentazocine at a dose of 17.5 mg/Kg. Adult albino mice and rats of either sex of six numbers in each group were under taken for study and evaluated by eddy’s hot plate and tail immersion method. The all doses of Acacia Senegal pod crude hydro-alcoholic extract were found to produce significant (P<0.05) analgesic activity. In eddy’s hot plate and tail immersion, both method showed significant activity (P<0.05) after 30 minutes. The result showed significant analgesic activity against stimuli.

Keywords: Acacia senegal pod, Crude hydro-alcoholic extract, Eddy’s hot plate method, Tail immersion method, Pentazocine.


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