DOI: 10.21276/ajptr
Mon, 25 Jun 2018

A Very Instantaneous & Novel Delivery of Nanosponges

Nabeela Rashee1*, K. Krishna Kumar2, Smitha.K.Nair2

1.Dept. of pharmaceutics, St James College of pharmaceutical sciences, chalakudy, Kerala,

2.St. James Hospital Trust Pharmaceutical Research Centre (DSIR recognized), chalakudy, Kerala


ABSTRACT

The development of nanoscience and its various technologies has tremendously helped to develop many dosage forms for various complicated diseases. This is a unique technology for the drug delivery containing micro porous beads loaded with drug material inside them. The nano sponge like materials are produced in order to improve the targeting characteristic along with a comfort to diminish the treats of ailments by using  mostly available drugs and their by helping to prevent most of the drug-protein degradation in the body. The development of these tiny discrete, porous and a colloidal mesh structure called as ‘nanosponges’ are preferable for topical, oral, inhalational deliveries. They are very small micronized structures of less than 1 µm. They act like a controlled and targeted material with an ease formulation and have a maximum stability. These micro molecules are synthesized from water soluble and bio erodible polymers. This tiny structure can stick, adhered or localizes to specific target receptors to produce controlled response. These materials must be focused in future and is a well promising material to be used in pharmaceutical sector. Their performance to entrap drugs or even to become complex for a desired release onto the site of action within a specific time without alteration in temperature is an advantage. In this review a brief summary of sponges with the introduction, advantages, disadvantages, preparation, loading, evaluation, and conclusion are discussed with a motto to include them in future drug developments.

Keywords: Nanosponges, nanotechnology, synthesis, preparation.


[PDF]   Viewed: 116   Downloaded: 40 DOI No: 10.21276/ajptr.2018.08.02.06
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