DOI: 10.21276/ajptr
Thu, 18 Oct 2018

Extraction of Mucilage as a Binder From the Petals OF Hibiscus Rosasinensis Linn and its Comparative Evaluation –In Vitro

Suchita Gokhale1*, Gaurav Dubey1, Pritam Khandave1, Shubhangi Kshirsagar

Ideal College of Pharmacy and Research, kalyan.


ABSTRACT

Hibiscus rosasinensis Linn are used in medicines in emollients and also it is used to treat burning sensations and skin disease. Mucilage of Hibiscus rosasinensis contains L‐rhamnose, D‐galactose, D‐galactouronic acid, and D‐glucuronic acid. The present article is trying to present an investigation is to extract the mucilage from the petals of flower of Hibiscus rosasinensis and use it in a paracetamol tablets as a binder. As the mucilage having granulating and binding properties so it is used in tablets, using paracetamol as a model drug. The Ph of mucilage was found to be 6.5 and all the physicochemical properties i.e. solubility and swelling index was studied. In this investigation wet granulation technique is used for the formation of granules using the above described mucilage which having the concentration of 2%, 5% and 7% w/v to use as a binder.’

Keywords: Hibiscus rosasinensis, Mucilage, binder, Tragacanth , Acacia

 


[PDF]   Viewed: 14   Downloaded: 26 DOI No: 10.21276/ajptr.2018.08.05.06
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