DOI: 10.21276/ajptr
Mon, 27 May 2019

Friedel-Craft Acylation of Phenols in 1-Ethyl-3-Methylimidazolium Tetrachloroaluminate Ionic Liquid.

Mahendra Sawant1*, Nandkishor Chandan1

1. Department of Chemistry, Siddharth college of ASC, Fort Mumbai, M.S. India


Through this review we would like to introduce clean and efficient method of most conventional Friedel-Craft acylation of phenols using Ionic liquid. This method has best results of acylated phenols in terms of quality and yields are concerned. The Friedel-Craft acylation is an everyday applicable industrial synthesis. Phenols are dihydric, trihydric as well as monohydric hydrocarbons used to undergo acylation. Acetyl chloride is best suitable reagent for aromatic C-acylation. Ionic liquid [EMIM][AlCl4] has best solvation and catalytic effect in the reaction.

Key Word: Friedel-Craft Acylation, Phenols, Ionic liquid [EMIM][AlCl4], Acetyl Chloride


[PDF]   Viewed: 154   Downloaded: 60 DOI No: 10.21276/ajptr.2018.08.05.09
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter